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U.S. Patents Awarded to Inventors in Maryland (Sept. 10)
(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service
Targeted News Service
ALEXANDRIA, Va., Sept. 10 -- The following federal patents were awarded to inventors in Maryland.
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Antibody Preparation Method Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Two inventors, including Kathleen F. Pirollo, Rockville, Md., and Esther H. Chang, Chevy Chase, Md., have invented a preparation method for antibody or antibody fragment-targeted cationic immunoliposome. The U.S. Patent was issued on Aug. 24 (No. 7,780,882).
The U.S. Patent and Trademark Office stated that the invention is a "method of preparing an antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex comprises the steps of (a) preparing an antibody or antibody fragment; (b) mixing said antibody or antibody fragment with a cationic liposome to form a cationic immunoliposome or with a cationic polymer to form a polyplex; and (c) mixing said cationic immunoliposome or said polyplex with a therapeutic or diagnostic agent to form said antibody- or antibody fragment-targeted cationic immunoliposome or polymer complex."
The patent was assigned to Georgetown University, Washington. The application was filed on April 2, 2002 (No. 10/113,927) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=47&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD.
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Anti-Terrorist Barrier System Developed by Germantown Inventor
ALEXANDRIA, Va., Sept. 9 -- Aris Mardirossian, Germantown, Md., has invented a method of securing a fixed confined area. The U.S. Patent was issued on Aug. 31 (No. 7,784,389).
The U.S. Patent and Trademark Office stated that "a system and/or method for securing areas (e.g. airport terminals, courtrooms, embassies, borders, property surrounding critical infrastructure, areas within cities/towns, etc.) against terrorists is provided. In certain example embodiments, a system and/or method is provided wherein individuals pass (e.g. walk, drive, etc.) through a gateway before gaining access to a secured area. Signals capable of detonating certain explosives that might be carried by the individuals passing through the gateway are emitted in or proximate the gateway. The gateway may be shielded to minimize damage to the surrounding areas. In certain example embodiments, arc currents are generated to trigger the detonation of explosives. In certain example embodiments, explosives may be detonated using cellular signals."
The patent was assigned to Technology Patents LLC, Derwood, Md. The application was filed on March 20, 2006 (No. 11/378,636) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=49&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Neovascularization Diseases Treatment System Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Four inventors, Yijia Liu, Gaithersburg, Md., Patrick Y. Lu, Rockville, Md., Martin C. Woodle, Bethesda, Md., and Frank Y. Xie, Germantown, Md., have invented methods for treatment of diseases involving unwanted neovascularization. The U.S. Patent was issued on Aug. 31 (No. 7,786,092).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states the invention consists of "compositions and methods are provided for treatment of diseases involving unwanted neovascularization (NV). The invention provides treatments that control NV through selective inhibition of pro-angiogenic biochemical pathways, including inhibition of the VEGF pathway gene expression and inhibition localized at pathological NV tissues. Tissue targeted nanoparticle compositions comprising polymer conjugates and nucleic acid molecules that induce RNA interference (RNAi) are provided. The nanoparticle compositions of the invention can be used alone or in combination with other therapeutic agents such as VEGF pathway antagonists. The compositions and methods can be used for the treatment of NV diseases such as cancer, ocular disease, arthritis, and inflammatory diseases."
The patent was assigned to Intradigm Corp., Palo Alto, Calif. The application was filed on April 9, 2009 (No. 12/420,907), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=31&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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NO.sub.X Emissions Control Method Co-Developed by Columbia Inventors
ALEXANDRIA, Va., Sept. 9 -- Five inventors, including John Allen Rudesill and Meenakshi Sundaram Krishnamoorthy, Columbia, Md.; and Timothy Dougan and Katherine W. Dougan, Pasadena, Md., have invented a method for controlling NO.sub.x emissions during a fluid catalytic cracking process. The U.S. Patent was issued on Aug. 24 (No. 7,780,935). The other co-inventor is George Yaluris, Park Ridge, Ill.
The U.S. Patents and Trademark Office stated the invention was a "process for the reduction of NO.sub.x emissions from a regeneration zone during a fluid catalytic cracking (FCC) process.... The process comprises contacting a hydrocarbon feedstock with a circulating inventory of an FCC cracking catalyst and a NO.sub.x reduction composition during an FCC process. The NO.sub.x reduction composition comprises at least one reduced nitrogen species component having the ability to reduce the content of reduced nitrogen species to molecular nitrogen under reducing or partial burn FCC conditions and at least one NO.sub.x reduction component having the ability to convert NO.sub.x to molecular nitrogen under oxidizing or full burn FCC conditions."
The patent was assigned to W.R. Grace & Co.-Conn., Columbia, Md. The application was filed on Feb. 23, 2006 (No. 11/886,114), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=46&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Amyloid Precursor Protein Reducing Agents Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Twelve inventors, including Nigel H. Greig, Phoenix, Md., Qiang-Sheng Yu, Lutherville, Md., Harold W. Holloway, Middle River, Md., Timothy T. Soncrant, Silver Spring, Md., Donald K. Ingram, Ellicott City, Md., and Arnold Brossi, Bethesda, Md., have invented agents useful for reducing amyloid precursor protein. The U.S. Patent was issued on Aug. 31 (No. 7,786,162). Other co-inventors are Tada Utsuki, West Chester, Pa., Anthony Giordano, Phoenixville, Pa., Gordon Powers, Malvern, Pa., Diane M. Davidson, Collegeville, Pa., Michael Sturgess, Quakertown, Pa., and Karen T.Y. Shaw, St. Laurent, Canada.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states the invention consists of "compounds and methods of administering compounds to a subject that can reduce .beta. amyloid precursor protein (APP) production and that is not toxic in a wide range of dosages. The present invention also provides non-carbamate compounds and methods of administering such compounds to a subject that can reduce .beta.APP production and that is not toxic in a wide range of dosages. It has been discovered that either the racemic or enantiomerically pure non-carbamate compounds can be used to decrease .beta.APP production."
The patent was assigned to Raptor Pharmaceutical Corp., Novato, Calif., and the National Institutes of Health. The application was filed on Jan. 21, 2009 (No. 12/357,115), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=30&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Sugar-Containing Hydrogel for Immobilization Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Five inventors, including Paul T. Charles, Bowie, Md., and Charles H. Patterson Jr., Glen Burnie, Md., have invented a sugar-containing hydrogel for immobilization. The U.S. Patent was issued on Aug. 31 (No. 7,785,770). Other co-inventors are Mark S. Spector, Springfield, Va., David A. Stenger, Herndon, Va., and Brett D. Martin, Washington.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states the invention involves the "use of sugar-containing hydrogels as very highly porous, aqueous support material for the immobilization of oligonucleotides, peptides, proteins, antigens, antibodies, polysaccharides, and other biomolecules for sensor applications. Unusually large sizes of interconnected pores allow large target molecules to pass rapidly into and through the gel and bind to immobilized biomolecules. Sugar-containing hydrogels have extremely low non-specific absorption of labeled target molecules, providing low background levels. Some hydrogel materials do not have this type of homogeneous interconnected macroporosity, thus large target molecules cannot readily diffuse through them. Additionally, they nearly always experience non-specific absorption of labeled target molecules, limiting their usefulness in sensor applications. A method is provided for preparing sugar polyacrylate hydrogels with functional chemical groups which covalently bond oligonucleotides and peptides. A method for copolymerizing acrylate-terminated oligonucleotides with sugar acrylate monomers and diacrylate cross-linking agents is also provided."
The patent was assigned to the U.S. Navy. The application was filed on May 19, 2006 (No. 11/444,819), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=37&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Recombinant Vaccine Against Botulinum Neurotoxin Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Six inventors, including Leonard A. Smith, Clarksburg, Md., Michael P. Byrne, New Market, Md., John L. Middlebrook, Middletown, Md., Michael A. Clayton, Mt. Airy, Md., and Douglas R. Brown, Gaithersburg, Md., have invented recombinant vaccine against botulinum neurotoxin. The U.S. Patent was issued on Aug. 31 (No. 7,786,285). The other co-inventor is Hugh Lapenotiere, Charlestown, W.Va.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Preparation and expression of synthetic genes encoding polypeptides containing protective epitopes of botulinum neurotoxin (BoNT). The invention is also directed to production of immunogenic peptides encoded by the synthetic genes, as well as recovery and purification of the immunogenic peptides from recombinant organisms. The invention is also directed to methods of vaccination against botulism using the expressed peptides."
The patent was assigned to the U.S. Army. The application was filed on May 19, 2006 (No. 11/437,212), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=27&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Thioether Cross-Link Macromolecules Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including Mark Schenerman, Reisterstown, Md., and Ziping Wei, North Potomac, Md., have invented macromolecules comprising at least one thioether cross-link. The U.S. Patent was issued on Aug. 31 (No. 7,786,273). The other co-inventor is Guillermo I. Tous, East Windsor, N.J.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Macromolecules comprising at least one thioether cross-link. A thioether cross-link comprising a single thioether bond between two residues of a macromolecule. The macromolecules of the invention can display enhanced stability, pharmaceutical properties and functional properties. In particular, the invention provides an isolated antibodies comprising at least one thioether cross-link that specifically bind to particular antigens. The present invention also provides a composition comprising a macromolecule substantially free of a denaturing reagent, wherein the macromolecule comprises at least one thioether cross-link. In addition, the present invention provides a method for producing the macromolecules and compositions of the invention."
The patent was assigned to Medimmune LLC, Gaithersburg, Md. The application was filed on March 14, 2006 (No. 11/375,810), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=28&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Cell Lysating Sonication Apparatus Co-Developed by Severna Park Inventor
ALEXANDRIA, Va., Sept. 9 -- Two inventors, including Phillip I. Belgrader, Severna Park, Md., have invented a method for lysing cells using sonication. The U.S. Patent was issued on Aug. 31 (No. 7,785,869). The other co-inventor is Bob Yuan, Belmont, Calif.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states a "sonication apparatus is directed to a microfluidic-based system to automate differential extraction of specific cell types within a mixed sample. The microfluidic-based system includes a sonication module for selective cell lysis, separating means to eliminate centrifugation, high surface area pillar chip modules to purify DNA from a cell lysate, and microfluidic circuitry to integrate the steps in an automated platform."
The patent was assigned to Microfluidic Systems Inc., Fremont, Calif. The application was filed on Feb. 9, 2006 (No. 11/352,108), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=35&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Curved Object Locating Method Co-Developed by North Bethesda Inventor
ALEXANDRIA, Va., Sept. 9 -- Four inventors, including Omid Kia, North Bethesda, Md., have invented a method for locating a curved object. The U.S. Patent was issued on Aug. 24 (No. 7,783,093). Other co-inventors are Arun Singh, North Wales, Pa., Edward Marandola, Gwynedd, Pa., and Uwe Mundry, Mauldin, S.C.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Method and apparatus for locating in a three dimensional data array an arcuate object having an axial extent, slices of data generally transverse to the axial extent of the object are selected. Rays generally radially of the arcuate object are selected within the slices. Crossing points where the rays cross the boundaries of the arcuate object are located. The position of the arcuate object is determined from the positions of the located points."
The patent was assigned to Imaging Sciences International LLC, Hatfield, Pa. The application was filed on May 20, 2006 (No. 11/437,524), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=21&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=(MD.INST.)&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Humanized Fc.Gamma.Riib Antibodies Using Systems Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Two inventors, Leslie S. Johnson, Darnestown, Md., and Ling Huang, Bethesda, Md., have invented humanized Fc.gamma.RIIB antibodies. The U.S. Patent was issued on Aug. 31 (No. 7,786,270).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Humanized Fc.gamma.RIIB antibodies, fragments, and variants thereof that bind human Fc.gamma.RIIB with a greater affinity than said antibody binds Fc.gamma.RIIA. The invention encompasses the use of the humanized antibodies of the invention for the treatment of any disease related to loss of balance of Fc receptor mediated signaling, such as cancer, autoimmune and inflammatory disease. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the humanized antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing the efficacy of a vaccine composition by administering the humanized antibodies of the invention. The invention encompasses methods for treating an autoimmune disease and methods for elimination of cancer cells that express Fc.gamma.RIIB."
The patent was assigned to MacroGenics Inc., Rockville, Md. The application was filed on May 25, 2007 (No. 11/754,015), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=29&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Backplanes Formation Process for Electro-Optic Display Co-Developed by Bowie Inventor
ALEXANDRIA, Va., Sept. 9 -- Eight inventors, including Kevin L. Denis, Bowie, Md., have invented a process for forming backplanes for an electro-optic display. The U.S. Patent was issued on Aug. 31 (No. 7,785,988). Other co-inventors are Nathan R. Kane and Andrew P. Ritenour, Arlington, Mass., Karl R. Amundson, Cambridge, Mass., Guy M. Danner, Somerville, Mass., Gregg M. Duthaler, Needham, Mass., Peter T. Kazlas, Sudbury, Mass., and Yu Chen, Milpitas, Calif.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Non-linear element is formed on a flexible substrate by securing the substrate to a rigid carrier, forming the non-linear element, and then separating the flexible substrate from the carrier. The process allows flexible substrates to be processed in a conventional fab intended to process rigid substrates. In a second method, a transistor is formed on a insulating substrate by forming gate electrodes, depositing a dielectric layer, a semiconductor layer and a conductive layer, patterning the conductive layer to form source, drain and pixel electrodes, covering the channel region of the resultant transistor with an etch-resistant material and etching using the etch-resistant material and the conductive layer as a mask, the etching extending substantially through the semiconductor layer between adjacent transistors. The invention also provides a process for forming a diode on a substrate by depositing on the substrate a first conductive layer, and a second patterned conductive layer and a patterned dielectric layer over parts of the first conductive layer, and etching the first conductive layer using the second conductive layer and dielectric layer as an etch mask. Finally, the invention provides a process for driving an impulse-sensitive electro-optic display."
The patent was assigned to E Ink Corp., Cambridge, Mass. The application was filed on Oct. 1, 2008 (No. 12/243,411), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=33&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Proliferative Disease Detection Method Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Four inventors, Victor V. Lobanenkov, Rockville, Md., Dmitri Loukinov, Germantown, Md., Ziedulla Abdullaev, Damascus, Md., and Svetlana Pack, North Potomac, Md., have invented a method of detecting a proliferative disease. The U.S. Patent was issued on Aug. 31 (No. 7,785,814).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states the invention relates to a "method of detecting a proliferative disease, such as a disease associated with the abnormal expression of BORIS, in a mammal comprising detecting antibodies to BORIS in a sample obtained from the mammal. The invention also provides BORIS polypeptides as well as compositions and kits comprising the BORIS polypeptides and methods of using the same. The invention further provides a method of inducing an immune response in a mammal using BORIS polypeptides."
The patent was assigned to the U.S. Department of Health and Human Services. The application was filed on Sept. 21, 2005 (No. 11/575,732), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=36&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Blocked Mercaptosilane Coupling Agent Production Process Co-Developed by Gaithersburg Inventor
ALEXANDRIA, Va., Sept. 9 -- Six inventors, including Prashant Joshi, Gaithersburg, Md., have invented a process for the production of blocked mercaptosilane coupling agents. The U.S. Patent was issued on Aug. 24 (No. 7,781,606). Other co-inventors are Richard W. Cruse, Yorktown Heights, N.Y., Eric R. Pohl, Mt. Kisco, N.Y., Antonio Chaves, Chappaqua, N.Y., W. Michael York, Concord, N.C., and Tiberiu L. Simandan, Marietta, Ohio.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Sulfur silane coupling agents containing multiple blocked mercapto groups which are in a state of reduced activity until activated. The coupling agents are advantageously used in rubber formulations, for example, for fabricating tires with low rolling resistance."
The patent was assigned to Momentive Performance Materials Inc., Albany, N.Y. The application was filed on Dec. 28, 2006 (No. 11/647,780) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=29&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD.
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Stabilized Liquid Anti-Respiratory Syncytial Virus Antibody Formulations Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Five inventors, including Christian B. Allan, Brookeville, Md., Stephen T. Chang, Frederick, Md., and Cynthia N. Oliver, North Potomac, Md., have invented stabilized liquid anti-respiratory syncytial virus antibody formulations. The U.S. Patent was issued on Aug. 31 (No. 7,785,592). Other co-inventors are Erica Shane, McLean, Va., and Benjamin S. Isaacs, Andover, Mass.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states that the invention provides "liquid formulations of SYNAGIS.RTM. or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS.RTM. or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS.RTM. or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention."
The patent was assigned to MedImmune LLC, Gaithersburg, Md. The application was filed on Oct. 1, 2007 (No. 11/906,543), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=40&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Rack Assembly for Animal Cages Co-Developed by Seaford Inventor
ALEXANDRIA, Va., Sept. 9 -- Six inventors, including George S. Gabriel, Seaford, Md., Neil E. Campbell, Eden, Md., Dale Murray, Elkton, Md., Rodney Gerringer; Belcamp, Md., and Bill Crites, Baltimore, have invented a rack assembly for housing animals in cages. The U.S. Patent was issued on Aug. 31 (No. 7,784,413). The other co-inventor is Lynn Irwin, Seaford, Del.
The U.S. Patent and Trademark Office stated that the invention consists of a "rack assembly for housing cages [that] comprise at least one shelf, the shelf having a shelf section comprising a runner capable of being positioned in a least a first position and a second position. The shelf section is constructed and arranged to accommodate two cages having a first and second widths when the runner is positioned in the first position. The shelf section is constructed and arranged to accommodate a single cage having a third width when the runner is in a second position, the first and second widths being less than the third width."
The patent was assigned to Lab Products Inc., Seaford, Del. The application was filed on Oct. 14, 2005 (No. 11/250,842) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=48&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Ballistic Single Flux Quantum Logic Apparatus Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Three inventors, Quentin P. Herr and Anna Y. Herr, both of Ellicott City, Md., and James E. Baumgardner, Odenton, Md., have invented an apparatus for ballistic single flux quantum logic. The U.S. Patent was issued on Aug. 24 (No. 7,782,077).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Single flux quantum (SFQ) signal transmission line powered by an alternating current (AC) power source. The AC power source supplies power to a transformer having a primary winding and a secondary winding. The primary winding receives the AC signal and the secondary winding communicates the signal to the SFQ transmission line. The transmission line can optionally include an input filter circuit for receiving the incoming SFQ pulse. The filter circuit can have a resistor and an inductor connected in parallel. In an alternative arrangement, the filter circuit can comprise of an inductor. A first Josephson junction can be connected to the filter circuit and to the secondary winding. The Josephson junction triggers in response to the incoming SFQ pulse and regenerates a pulse signal in response to a power discharge from the secondary winding."
The patent was assigned to Northrop Grumman Systems Corp., Los Angeles. The application was filed on May 7, 2009 (No. 12/437,510), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=28&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Particle Image Velocimetry System Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Three inventors, Ilko K. Ilev, Rockville, Md., Ronald A. Robinson, Germantown, Md., and Ronald W. Waynant, Clarksville, Md., have invented an illumination system for a particle image velocimetry system. The U.S. Patent was issued on Aug. 31 (No. 7,787,106).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states that the invention relates to an illumination system for a particle image velocimetry system that "has an illumination source, a hollow tapered optical funnel arranged to receive illumination light from the illumination source, a hollow optical waveguide optically coupled to an output end of the hollow tapered optical funnel, and a beam shaping optical system optically coupled to an output end of the hollow optical waveguide. The illumination system is constructed to provide a light sheet to illuminate particles within a fluid under observation. A particle image velocimetry system has such an illumination system."
The patent was assigned to the U.S. Department of Health and Human Services. The application was filed on Oct. 30, 2006 (No. 11/589,310), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=24&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Single Photon Emission Computed Tomography Imaging Apparatus Co-Developed by Baltimore Inventor
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including Benjamin M.W. Tsui, Baltimore, have invented a multi-aperture single photon emission computed tomography imaging apparatus. The U.S. Patent was issued on Aug. 31 (No. 7,786,444). Other co-inventors are Douglas J. Wagenaar, Westlake Village, Calif., and Bradley E. Patt, Sherman Oaks, Calif.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Methods and systems for improving image quality of single photon nuclear imaging systems, such as single photon emission computed tomography (SPECT) systems for imaging of an object under study, such as small objects including small animals of different sizes using synthetic apertures. The methods and systems include processes and instrumentations for high-resolution, high detection efficiency leading to lower image noise and artifact-free synthetic aperture single photon nuclear images, such as SPECT images. Also, the method and systems provide design parameters, hardware settings, and data acquisition processes for optimal imaging of objects having different sizes."
The patent was assigned to Gamma Medica-Ideas Inc., Northridge, Calif. The application was filed on Nov. 16, 2007 (No. 11/985,820), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=26&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Azeotropic Compositions with Fluorinated Compounds Co-Developed by Elkton Inventor
ALEXANDRIA, Va., Sept. 9 -- Two inventors, including Barbara Haviland Minor, Elkton, Md., have invented an azeotropic compositions comprising fluorinated compounds for cleaning applications. The U.S. Patent was issued on Aug. 31 (No. 7,786,061). The other co-inventor is Melodie A. Schweitzer, Wilmington, Del.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Compositions comprising fluorinated olefins or fluorinated ketones, and at least one alcohol, halocarbon, hydrofluorocarbon, or fluoroether and combinations thereof. In one embodiment, these compositions are azeotropic or azeotrope-like. In another embodiment, these compositions are useful in cleaning applications as a degreasing agent or defluxing agent for removing oils and/or other residues from a surface."
The patent was assigned to E.I. du Pont de Nemours and Co., Wilmington, Del. The application was filed on Oct. 9, 2009 (No. 12/576,273), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=32&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Tamper Respondent System Co-Developed by Elkton Inventors
ALEXANDRIA, Va., Sept. 9 -- Four inventors, including Karl Chan and Harold Wylie, Elkton, Md., have invented a tamper respondent system. The U.S. Patent was issued on Aug. 31 (No. 7,787,256). Other co-inventors are Brent Lewis, Middletown, Del., and Dale Murray, Mt. Joy, Pa.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Tamper respondent system having: a physical volume containing an electronic device to be protected; and at least partially conductive surface proximate to the electronic device; and a tamper respondent sensor over the electronic device (the sensor comprising: a flexible, dielectric substrate; conductive traces on the substrate; a porous insulating layer having pores over the conductive traces; and adhesive within said pores of said porous insulating layer), wherein the adhesive is in contact with both the substrate and the at least partially conductive surface through the porous insulating layer."
The patent was assigned to Gore Enterprise Holdings Inc., Newark, Del. The application was filed on Aug. 10, 2007 (No. 11/836,870), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=22&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Bovine Immunodeficiency Virus Based Vectors Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including Tianci Luo, Clarksville, Md., and Michael Kaleko, Potomac, Md., have invented bovine immunodeficiency virus based vectors. The U.S. Patent was issued on Aug. 31 (No. 7,785,877). The other co-inventor is Robert Berkowitz, San Francisco.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Bovine immunodeficiency virus (BIV) constructs encompassing BIV combination vectors, BIV vectors and BIV packaging vectors and particularly the invention pertains to a three vector system comprising: a) a BIV vector construct including a deoxyribonucleic acid (DNA) segment from a BIV genome, a packaging sequence to package ribonucleic acid into virions; a promoter operably linked to the DNA segment; and a transgene operably linked to a second promoter; b) a BIV packaging vector construct comprising a BIV DNA sequence fragment comprising at least a gag gene or pol gene of BIV; a promoter operably linked to the BIV DNA fragment; and a polyadenylation sequence located downstream of the BIV DNA fragment; and c) an expression vector construct comprising a gene encoding a viral surface protein. Also provided is a method for transferring a gene of interest into a mammalian cell."
The patent was assigned to Novartis A.G., Basel, Switzerland. The application was filed on March 8, 2005 (No. 11/076,399), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=34&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Multicurrency Transaction System Co-Developed by Bethesda Inventor
ALEXANDRIA, Va., Sept. 9 -- Seven inventors, including Stephen David Crocker, Bethesda, Md., have invented a method for multicurrency transactions. The U.S. Patent was issued on Aug. 31 (No. RE41,619). Other co-inventors are Brian Paul Boesch, Herndon, Va., Alden Sherburne Hart Jr., Arlington, Va., Andrew Jackson, Falls Church, Va., Denise Marie Paredes, Centreville, Va., Donald Eggleston Eastlake III, Carlisle, Mass., and Robert A. Lindenberg, Sudburn, Mass.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "System and method for determining approval of a multi-currency transaction between a customer and a merchant over a network. The system includes a customer computer which is connected to a communication network, a merchant computer which is connected to the communication network, and a server connected to both the customer computer via the communication network and to the merchant computer via the communication network. The customer computer includes a first set of data which contains an amount the customer is willing to pay the merchant for a product in a first currency. The merchant computer includes a second set of data which contains a product price at which the merchant agrees to sell the product in a second currency. The server receives the first set of data and the second set of data. The server then converts the amount in the first currency into a converted amount in the second currency. The server approves the transaction if the converted amount in the second currency is within a risk range of the product price in the second currency in accordance with current exchange rates. Once the transaction is approved, the approving entity may settle the transaction at its discretion thereby bearing the risk associated with currency exchange. The parties, however, incur no risk. The customer will pay the amount in the first currency and the merchant will receive the price in the second currency. These are values known and agreed to by the parties at the time of the transaction."
The patent was assigned to PayPal Inc., San Jose, Calif., and PayPal International Ltd., Dublin, Ireland. The application was filed on March 18, 2003 (No. 10/390,540), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Hazardous Materials Detection System Co-Developed by Kensington Inventor
ALEXANDRIA, Va., Sept. 9 -- Seven inventors, including Allen M. Jones, Kensington, Md., have invented a system for detecting hazardous materials. The U.S. Patent was issued on Aug. 31 (No. RE41,591). Other co-inventors are Christopher J. Tatar and Michael W. Finney, both of Endicott, N.Y., Michael A. Heaton, Owego, N.Y., John T. Swider, Port Crane, N.Y., Clifford A. Megerle, Thousand Oaks, Calif., and Barry Wake, Remington, Va.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "System and method for detecting contaminants in or on objects, having a movably mounted container for holding objects and having a plurality of perforations and an entrance opening through which objects may be placed into the container. A housing encloses the container and forms a barrier to ambient air. There is a sealable opening for inserting and removing objects from the container. A drive assembly moves the container within the housing to move objects therein for emitting particles which are in or on such object. There is an air stream for moving air through the housing and container to entrain any emitted particles into the air stream and a sensor for sensing contaminants in the air stream and providing a signal when a contaminant is sensed. The container can be a rotatable cage or a vibrating box. In the method, there is a chamber provided which may be sealed with respect to ambient air to create an enclosed atmosphere. A plurality of objects are loaded into or onto a perforated container disposed within the enclosed atmosphere and an air stream is created within the enclosed atmosphere. The objects are agitated to cause them to emit particles therefrom into the air stream .Iadd.which .Iaddend.is tested to determine whether it contains any contaminants. If so, a signal is provided."
The patent was assigned to Lockheed Martin Corp., Bethesda, Md. The application was filed on May 13, 2008 (No. 12/119,833), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=2&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Photonic Waveform Generator Co-Developed by Waldorf Inventor
ALEXANDRIA, Va., Sept. 9 -- Two inventors, including Jason D. McKinney, Waldorf, Md., have invented a photonic waveform generator. The U.S. Patent was issued on Aug. 31 (No. 7,787,779). The other co-inventor is Andrew M. Weiner, West Lafayette, Ind.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Photonic waveform generator and system is described. The photonic waveform generator is used in produce an electrical pulse having arbitrarily controllable temporal characteristics in a Fourier transform (FT) pulse shaper or a direct space-to-time (DST) photonic generator. The electrical pulse signal may be used in a radar, a telecommunications system or other electrical apparatus where the spectral and temporal characteristics of the signal are be optimized with respect to specific system needs, such as spectral occupancy, peak-to-average power, minimum pulse duration, target-to-clutter ratio, target type discrimination, and the like."
The patent was assigned to Purdue Research Foundation, West Lafayette, Ind. The application was filed on May 4, 2006 (No. 11/418,585), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=18&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Ornamental Design for Multi-Bollard Barrier Developed by Potomac Inventor
ALEXANDRIA, Va., Sept. 9 -- Gerald Skalka, Potomac, Md., has invented an ornamental design for a multi-bollard barrier. The U.S. Patent was issued on Aug. 31 (No. D622,873).
The patent was assigned to Secure Site Design LLC, Potomac, Md. The application was filed on March 25, 2010 (No. D/358,311) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=3&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Transfer Configuration Descriptor Production Method Co-Developed by Frederick Inventor
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including David Q. Bell, Frederick, Md., have invented a method of generating a transfer configuration descriptor. The U.S. Patent was issued on Aug. 31 (No. 7,788,422). Other co-inventors are Filip Moerman, Tourrettes-sur-Loop, France, and Pierre Bertrand, Antibes, France.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states the invention relates to a method that "includes generating a transfer configuration descriptor ("TCD"), the TCD includes information pertaining to data to be transferred. The method further includes dynamically configuring a direct memory access ("DMA) channel based on the TCD without using a central processing unit and transferring a group of data blocks by way of the DMA channel."
The patent was assigned to Texas Instruments Inc., Dallas. The application was filed on April 25, 2005 (No. 11/115,014), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=10&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Performance Enhancing Proxy Network Protocol Retransmission Implementing Method Developed by Gaithersburg Inventor
ALEXANDRIA, Va., Sept. 9 -- Anil Agarwal, Gaithersburg, Md., has invented a method of implementing a retransmission protocol in a performance enhancing proxy network. The U.S. Patent was issued on Aug. 31 (No. 7,787,372).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states that the invention involves the "integration of an improved retransmission protocol into a performance enhancing proxy for degraded communication links. Various embodiments of the invention include congestion control, window size adjustment algorithms, connection negotiation features, and connection establishment acceleration features."
The patent was assigned to Viasat Inc., Carlsbad, Calif. The application was filed on Dec. 12, 2005 (No. 11/298,612), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=21&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Ornamental Design for Handheld Electronic Stethoscope Developed by Adelphi Inventor
ALEXANDRIA, Va., Sept. 9 -- Verlin Alexander, Adelphi, Md., has invented an ornamental design for handheld electronic stethoscope. The U.S. Patent was issued on Aug. 31 (No. D622,844).
The application was filed on Nov. 25, 2009 (No. D/350,969) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=4&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Automated Property Valuation Adjustment System Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Four inventors, including Eric L. Rosenblatt, Derwood, Md., Mark Y. An, North Potomac, Md., and Hong Gao, Columbia, Md., have invented a system for automated property valuation adjustment. The U.S. Patent was issued on Aug. 31 (No. 7,788,186). The other co-inventor is Linghua Peng, Reston, Va.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states methods are provided for "removing systematic bias from property value predictions obtained using automated property valuation models. The systematic bias is removed by deriving monthly adjustment factors that are location-specific. The monthly adjustment factors are obtained by comparing newly obtained purchase transaction data to model-generated valuations of properties in a base valuation database. The newly obtained purchase transactions may be obtained from newly obtained data on recently completed purchase transactions and loan application data on future purchase transactions. The monthly adjustment factors are applied to the property valuations in the base valuation database to obtain adjusted property values having reduced bias and thus improved accuracy."
The patent was assigned to Fannie Mae. The application was filed on March 9, 2005 (No. 11/077,547), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=12&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Analytes Sensing Fiber Optic Device Producing Method Co-Developed by Monkton Inventor
ALEXANDRIA, Va., Sept. 9 -- Nine inventors, including John D. DeNuzzio, Monkton, Md., have invented a method of producing a fiber optic device for sensing analytes. The U.S. Patent was issued on Aug. 31 (No. 7,787,923). Other co-inventors are Javier Alarcon, J. Bruce Pitner and Douglas B. Sherman, Durham, N.C.; Kristin Weidemaier, Raleigh, N.C.; Terry J. Amis, Cary, N.C.; Ross W. Jacobson, Hillsborough, N.C.; Steven Keith, Chapel Hill, N.C.; and Christopher C. Herdman, Chappaqua, N.Y.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states that the device is "for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel."
The patent was assigned to Becton Dickinson & Co., Franklin Lakes, N.J. The application was filed on Oct. 19, 2004 (No. 10/967,220), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=14&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Temperature Sensing Fabric Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Four inventors, including Lynn E. Lynam, Bel Air, Md., and Lawrence G. Ten Eyck, Ellicott City, Md., have invented a temperature sensing fabric. The U.S. Patent was issued on Aug. 31 (No. 7,787,726). Other co-inventors are Hua Xia, Altamont, N.Y., and Kung-Li J. Deng, Waterford, N.Y.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Blanket or article of wearing apparel for a subject such as an infant. A fiber optic temperature sensing element is integrated into the fabric by a process such as weaving. The temperature sensing element is a optic fiber having inscribed therein one or more fiber Bragg grating sensors such that a light is introduced into the optic fiber and that light directed onto the subject at a grating interface. A return light signal is received, either by a reflectance mode or a transmission mode, where the return light signal has a wavelength shift indicative of the temperature of the subject by Bragg resonant effect. Higher temperature sensitivity is obtained with a metal material of a high thermal expansion coefficient that is coated around the fiber sensor cladding."
The patent was assigned to General Electric Co., Schenectady, N.Y. The application was filed on March 14, 2007 (No. 11/717,951), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=19&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Ornamental Design for Vine Fingerboard Inlay Developed by Laurel Inventor
ALEXANDRIA, Va., Sept. 9 -- Bruce Jacob, Laurel, Md., has invented an ornamental design for a vine fingerboard inlay. The U.S. Patent was issued on Aug. 31 (No. D622,758).
The application was filed on May 5, 2009 (No. D/336,526) and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=5&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Ornamental Design for Wrench Co-Developed by Baltimore Inventor
ALEXANDRIA, Va., Sept. 9 -- Two inventors, including Thomas Murray, Baltimore, have invented an ornamental design for a wrench. The U.S. Patent was issued on Aug. 31 (No. D622,566). The other co-inventor is Jon Salerno, New Boston, N.H.
The patent was assigned to Black & Decker Inc., Newark, Del. The application was filed on March 15, 2010 (No. D/357,626), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=6&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD.
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Throttling Electronic Communications Systems Co-Developed by Potomac Inventor
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including Mark J. Muehl, Potomac, Md., have invented throttling electronic communications from one or more senders. The U.S. Patent was issued on Aug. 31 (No. 7,788,329). Other co-inventors are Joseph G. Barrett, Oak Hill, Va., and Todd M. Palino, Cambridge, Mass.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Number and/or frequency of electronic data communications received from a sender or group of senders during a period of time may be monitored (e.g., counted). When more than a threshold number of electronic communications are communicated by the sender during the period of time, an ability of the sender to communicate messages may be affected."
The patent was assigned to AOL Inc., Dulles, Va. The application was filed on Jan. 12, 2006 (No. 11/330,340), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=11&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Magnetic Resonance Imaging Method Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 9 -- Three inventors, Reza Nezafat, Bethesda, Md., Ronald Ouwerkerk, Baltimore, and Matthias Stuber, Ellicott City, Md., have invented a magnetic resonance imaging method. The U.S. Patent was issued on Aug. 31 (No. 7,787,930).
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Zadiabatic pulses that define an amplitude modulation and a frequency modulation are applied in a sequence of pulses to obtain a T.sub.2 weighted magnetic resonance image. Such an adiabatic T.sub.2 prep sequence typically includes a first 90.degree. pulse, an even number of adiabatic pulses, and a second 90.degree. pulse. Adiabatic pulses can be selected based on function pairs, or can be defined numerically. A magnetic resonance imaging (MRI) system includes a library of adiabatic pulse waveforms, and is configured to select a waveform and apply a radio-frequency magnetic field based on the selected pulse waveform."
The patent was assigned to the U.S. Department of Health and Human Services and Johns Hopkins University, Baltimore. The application was filed on June 6, 2005 (No. 11/147,151), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=13&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Ultra Low Power Radio Frequency Link Co-Developed by Kensington Inventor
ALEXANDRIA, Va., Sept. 9 -- Three inventors, including Edward A. Page, Kensington, Md., have invented an ultra low power radio frequency link. The U.S. Patent was issued on Aug. 31 (No. 7,787,846). Other co-inventors are Avetis Ioannisyan, Hudson, N.H., and Kenneth R. Erikson, Henniker, N.H.
An abstract of the invention, published by the U.S. Patents and Trademark Office, states: "Radio frequency (RF) system is capable of transmitting and receiving sensor data using an ultra low power narrowband RF signal. The system handles frequency drift and other problems inherent in such a system through a spectrogram statistical analysis, dynamic programming, and narrowband filtering."
The application was filed on Sept. 8, 2005 (No. 11/222,425), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=17&f=G&l=50&co1=AND&d=PTXT&s1=20100831.PD.&s2=%28MD.INST.%29&OS=ISD/08/31/2010+AND+IS/MD&RS=ISD/08/31/2010+AND+IS/MD
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Controlled Release Dosage Forms Co-Developed by Potomac Inventor
ALEXANDRIA, Va., Sept. 10 -- Two inventors, including Paul Maes, Potomac, Md., have invented a monolithic coating for obtaining controlled release of drugs from oral dosage forms. The U.S. Patent was issued on Aug. 24 (No. 7,780,987). The other co-inventor is Fang Zhou, Centreville, Va.
The U.S. Patents and Trademark Office, states "the invention provides stable controlled release monolithic coating compositions for use in coating pharmaceutical oral dosage forms comprising a polyglycol having a melting point greater than 55 degree Celsius and an aqueous dispersion of a neutral ester copolymer lacking functional groups."
The patent was assigned to Biovail Laboratories International SRL, St. Michael, Barbados. The application was filed on Feb. 21, 2003 (No. 10/370,109), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=42&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Magnetic Resonance Analytes Detection System Co-Developed by Baltimore Inventor
ALEXANDRIA, Va., Sept. 10 -- Four inventors, including Terry J. Henderson, Baltimore, have invented a magnetic resonance system and method to detect and confirm analytes. The U.S. Patent was issued on Aug. 24 (No. 7,781,228). Other co-inventors are Suresh M. Menon, San Diego; David E. Newman, Poway, Calif.; and J. Manuel Perez, Orlando, Fla.
The U.S. Patents and Trademark Office, states that "a system and method are provided to detect target analytes based on magnetic resonance measurements. Magnetic structures produce distinct magnetic field regions having a size comparable to the analyte. When the analyte is bound in those regions, magnetic resonance signals from the sample are changed, leading to detection of the analyte."
The patent was assigned to Menon & Associates Inc., San Diego. The application was filed on Jan. 20, 2006 (No. 11/335,995), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=37&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Artificial Invaplex Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 10 -- Three inventors, including Edwin V. Oaks, Gambrills, Md.; Kevin R. Turbyfill, Odenton, Md.; and Robert W. Kaminski, Germantown, Md., have invented an artificial Invaplex complex. The U.S. Patent was issued on Aug. 24 (No. 7,780,966).
The U.S. Patents and Trademark Office, states that an "artificial invasin complex is prepared from purified or recombinantly prepared invasins and gram negative bacteria lipopolysaccharides. Typically, Invasion plasmid antigen B (IpaB) is mixed with Invasion plasmid antigen C (IpaC) to form a IpaB:IpaC complex. This invasin protein complex is then mixed with the lipopolysaccharide to form an artificial invasin complex. Additional bioactive molecules can be incorporated into the complex during manufacture. This artificial invasin complex is similar in function to native Invaplex 24 or Invaplex 50. The artificial invasin complex has superior immunogenicity properties relative to the native complex and can be tailor made. Its method of preparation lends itself to scale up. The artificial invasin complex can facilitate transport of biomolecules, therapeutics and antibiotics across cell membranes in a manner similar to native Shigella Invaplex."
The patent was assigned to the United States of America as represented by the Secretary of the Army, Washington. The application was filed on March 27, 2007 (No. 11/727,486), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=43&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=(MD.INST.)&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Genomic Screening Methods Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 10 -- Four inventors, including David Sidransky, Stephen B. Baylin and Hiromu Suzuki, Baltimore; and James Herman, Lutherville, Md., have invented methods of detecting tumor suppressor genes that are epigenetically silenced in cancer cells. The U.S. Patent was issued on Aug. 24 (No. 7,781,161).
The U.S. Patents and Trademark Office, states "methods of genomic screening to identify epigenetically silenced genes, including epigenetically silenced tumor suppressor genes are provided. Also provided are methods of detecting a cancer, for example, an esophageal squamous cell carcinoma or a head and neck squamous cell carcinoma, as are methods of treating a subject having such a cancer."
The patent was assigned to Johns Hopkins University School of Medicine, Baltimore. The application was filed on March 7, 2003 (No. 10/383,864), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=41&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Renal Diseases Diagnosing Method Co-Developed by Potomac Inventors
ALEXANDRIA, Va., Sept. 10 -- Four inventors, including Thomas C. Hart and Patricia Suzanne Hart, Potomac, Md., have invented a method of diagnosing renal diseases or predispositions. The U.S. Patent was issued on Aug. 24 (No. 7,781,164). Other co-inventors are Michael Gorry, Pittsburgh, and Anthony J. Bleyer, Winston-Salem, N.C.
The U.S. Patents and Trademark Office, states the invention provides a "method of diagnosing a disease or a predisposition to contract a disease by assaying for mutations of uromodulin (UMOD) within a test subject or patient. The presence of a mutation in the UMOD supports a diagnosis of a disease or a predisposition to contract a disease within the patient."
The patent was assigned to University of Pittsburgh - of the Commonwealth System of Higher Education, Pittsburgh; and Wake Forest University, Winston-Salem, N.C. The application was filed on April 23, 2005 (No. 11/112,327), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=40&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Nanoparticles Controllable Deposition System Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 10 -- Five inventors, including Michael R. Zachariah, Potomac, Md.; De-Hao Tsai, Silver spring, Md.; Raymond J. Phaneuf, College Park, Md.; Timothy D. Corrigan, Laurel, Md.; and Soo H. Kim, Rockville, Md., have invented a system for controllable deposition of nanoparticles on a substrate. The U.S. Patent was issued on Aug. 24 (No. 7,781,350).
The U.S. Patents and Trademark Office, states that "in a method and system for controllable electrostatic-directed deposition of nanoparticles from the gas phase on a substrate patterned to have p-type and n-type (p-n) junction(s), a bias electrical field is reversely applied to the p-n junction, so that uni-polarly charged nanoparticles are laterally confined on the substrate by a balance of electrostatic, van der Waals and image forces and are deposited on a respective p-doped or n-doped regions of the p-n junction when the applied electric field reaches a predetermined strength. The novel controllable deposition of nanoparticles employs commonly used substrate architectures for the patterning of an electric field attracting or repelling nanoparticles to the substrates and offers the opportunity to create a variety of sophisticated electric field patterns which may be used to direct particles with greater precision."
The patent was assigned to University of Maryland, College Park, Md. The application was filed on Feb. 24, 2006 (No. 11/360,440), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=36&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Tumor Suppressor Semaphorin Polypeptide SEMA3B Co-Developed by Rockville Inventor
ALEXANDRIA, Va., Sept. 10 -- Four inventors, including Michael Lerman, Rockville, Md., have invented semaphorin polypeptide SEMA3B as a tumor suppressor. The U.S. Patent was issued on Aug. 24 (No. 7,781,413). Other co-inventors are Yoshio Tomizawa, Takasaki, Japan; Yoshitaka Sekido, Nagoya, Japan; and John Minna, Dallas.
The U.S. Patents and Trademark Office, states "the present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods for treatment and diagnosis of cancer."
The patent was assigned to the Board of Regents of the University of Texas System, Austin, Texas. The application was filed on Oct. 31, 2002 (No. 10/285,351), and the document is available at: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=35&f=G&l=50&co1=AND&d=PTXT&s1=20100824.PD.&s2=%28MD.INST.%29&OS=ISD/08/24/2010+AND+IS/MD&RS=ISD/08/24/2010+AND+IS/MD
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Cancer Treatment Methods Co-Developed by Maryland Inventors
ALEXANDRIA, Va., Sept. 10 -- Six inventors, including Frank Y. Xie and Jun Xu, Germantown, Md.; Yijia Liu and Quinn Q. Tang, Gaithersburg, Md.; Patrick Y. Lu, Rockville, Md.; and Martin C. Woodle, Bethesda, Md., have invented methods for treating cancers by manipulating a target gene expression. The U.S. Patent was issued on Aug. 24 (No. 7,781,414).
The U.S. Patents and Trademark Office, states "the present invention relates to methods for treating cancers by manipulating a target gene expression by up-regulation, silencing and/or down-regulation of the gene, such as epidermal growth factor receptor-related protein (EGFR-RP), tumor rejection antigen-1 (TRA-1), epidermal growth factor 8 protein (MFGE8), Tumor necrosis factor ligand super family member 13 (TNFSF13)and zinc finger protein 236 (ZFP236), respectively. The methods are useful in treating cancers and/or inhibiting tumor growth by enhancing expression of a gene that is validated as a target such as ICT1030, for protein, peptide drug and gene therapy modalities; or by ribonucleic acid interference to silence and/or down-regulate targets such as ICT1024, ICT1025 and
For more information about Targeted News Service products and services, please contact: Myron Struck, editor, Targeted News Service LLC, Springfield, Va., 703/304-1897; editor@targetednews.com; http://targetednews.com.
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